A resurgent Serena Williams overcame a strong challenge from fellow-American Meghann Shaughnessy, winning 6-7, 6-1, 6-4.
However, French Open champion Anastasia Myskina's run of miserable form continued when she was beaten by Switzerland's Patty Schnyder.
Roger Federer and Serena Williams booked a second round berth, while Robin Soderling was booted out, during the Australian Open on Tuesday.
The 23-time Grand Slam champion has retorted to former tennis ace John McEnroe's comments, saying she would struggle on the men's circuit.
A battle-tested Serena Williams booked her spot in the semi-finals of the Toronto Cup on Friday after overcoming a sluggish start to grind out a 4-6, 6-3, 6-2 win over Czech Lucie Safarova.
Serena Williams could wow the Wimbledon public next year by reviving her skin-tight, all-in-one catsuit in white.
'I don't know. It's tough to explain my emotion right now. Maybe tomorrow morning I can tell you something, but now it's amazing'
Canadian teenager Eugenie Bouchard swatted aside an out-of-sorts Serena Williams 6-2, 6-1 at the Hopman Cup in Perth on Tuesday.
Wimbledon champions Roger Federer and Serena Williams were on course for further success at the All-England Club after booking their places in the Olympic singles semi-finals on Thursday.
'The world is suffering in general, so we can't complain'
Serena Williams pulled out of next week's Nasdaq Open in Miami on Friday, citing a knee injury and lack of training.
Daniela Hantuchova said that Serena did not need the medical-timeout during their third-round match.
Former World No. 1 Serena Williams gave the United States a commanding 2-0 lead over Belarus in their Fed Cup tie on Saturday after top ranked Victoria Azarenka was unable to compete for the eastern Europeans because of a sore lower back.
Tennis World No. 1 Serena Williams found herself in trouble with security officials at the PGA Tour's Honda Classic on Friday after she tried to photograph Tiger Woods.
Breeze though the outfits that caught the maximum shutterbugs at the final Grand Slam of the year.
Serena Williams capped off yet another successful day at Wimbledon for America's premier tennis family as she followed up her singles triumph by winning the doubles title with sister Venus on Saturday.
Venus worde down Lindsay Davenport while Clijsters rallied to beat Silvia Farina Elia in women's quarter-final matches.
Serena Williams, who racked up her 500th match win with the victory, said her ankle is still causing her problems, a potential issue for tougher tests ahead.
World No 1 and top seed Serena Williams racked up the 50th title of her 18-year career when she thumped Maria Sharapova 6-1, 6-4 to defend her Madrid Open crown on Sunday.
A round-up of the important matches at Wimbledon on Friday.
World number two Serena Williams brushed aside qualifier Lucie Safarova 6-3, 6-2 on Friday to reach the semi-finals of the Toronto Cup and set up a mouth-watering clash with Elena Dementieva.
Serena Williams is prepared to go without another victory this year, as long as she mounts a successful title defence at next week's U.S. Open.
Victoria Azarenka suffered a stunning meltdown and blew three match points against world number one Serena Williams before losing 7-6(5), 3-6, 7-6(1) in the third round of the Madrid Open on Wednesday.
Serena was drawn on Friday to play doubles in a potentially decisive fifth rubber in this week's Fed Cup first round tie against the Netherlands in what will be her first competitive match in over a year. The doubles rubber, which is scheduled for Sunday on an indoor hard court in Asheville, North Carolina, will be played even if one side clinches the best-of-five match series through the opening four singles matches.
Serena Williams powered into the fourth round of the Australian Open on Saturday with a 6-2, 6-1 demolition of Dayana Yastremska then consoled the Ukrainian teenager after leaving her in tears.
French Open champion Justine Henin enjoyed a swift 60-minute workout to overcome Russia's Vera Dushevina to enter the third round.
Serena Williams started her 2010 season in the same devastating fashion in which she ended 2009, thrashing Spain's Marie Jose Martinez Sanchez 6-1, 6-2 in the second round of the Sydney International on Tuesday.
Both will play their second-round singles matches on Thursday.
World number one Serena Williams kept her Wimbledon title defence on track on Sunday, downing Germany's Annika Beck 6-3, 6-0 with a crushing display of power and booming serves to chalk up her 300th grand slam victory.
Serena Williams has used her painful defeat at the French Open to spur her on at Wimbledon.\n\n
Serena Williams likes proving people wrong and intends to surprise the sceptics at next month's French Open.
Novak Djokovic has declined to disclose his vaccination status despite everyone at Melbourne Park needing to be inoculated against COVID-19.
While her career has featured a number of highs -- she has won two doubles Grand Slam titles and 11 WTA titles, including the Cincinnati Masters -- Garcia said she has become fixated on what she sees as her failures.
The International Tennis Federation hosted the ITF World Champions Dinner in Paris on Tuesday and World No 1s Novak Djokovic and Serena Williams were honoured at the annual function.
She becomes only the fifth woman to hold all four grand slam titles at the same time.
Serena Williams laid down an imposing marker ahead of the first grand slam of the year by powering to a 6-4, 7-5 victory over Australian Open champion Victoria Azarenka at the Brisbane International.